Keep an eye on Closely (one)ribociclib will raise the amount or result of ergotamine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
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saquinavir will increase the level or effect of ergotamine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
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istradefylline will raise the degree or impact of ergotamine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
Keep an eye on Intently (1)glycerol phenylbutyrate will reduce the level or influence of ergotamine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
apalutamide will reduce the extent or effect of ergotamine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Coadministration of apalutamide, a powerful CYP3A4 inducer, with medication which might be CYP3A4 substrates can lead to decreased exposure to these drugs.
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glycerol phenylbutyrate will lower the extent or result of ergotamine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. Glycerol phenylbutyrate is usually a weak inducer of CYP3A4. Keep an eye on for reduced efficacy of CYP3A4 substrates which have a narrow therapeutic website index.
letermovir boosts levels of ergotamine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration of letermovir and ergot alkaloids is contraindicated because of risk of ergotism.
duvelisib will enhance the level or outcome of ergotamine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Carefully. Coadministration with duvelisib raises AUC of a delicate CYP3A4 substrate which may increase the hazard of toxicities of such medications.
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